HTX M5 Sprayer

HTX M5 Sprayer

Equipment overview

The HTX M5 Sprayer is an advanced, automated matrix deposition system designed primarily for Mass Spectrometry Imaging (MSI) applications, such as MALDI-MSI sample preparation. Built on the foundation of previous models, the M5 features an upgraded chassis, high-velocity XY stage, and an integrated heated sample tray/drawer.

Major applications

Its primary purpose is to apply a precise, highly uniform coating of matrix solutions (or enzymes like trypsin for on-tissue digestion) onto tissue samples or MALDI plates. This guarantees fine crystal formation and optimal analyte extraction while minimizing analyte delocalization, yielding high spatial resolution and robust relative quantification.

Specifications

Flow Rate Range
0.050 to 1.000 mL/min
Gas Pressure
8 psi to 30 psi (Nitrogen)
Nozzle Velocity
Up to 5,600 mm/min via the High-Velocity XY stage
Deposition Consistency
± 3% by weight across the total sample area
Sample Preparation Time
Typically 2 to 18 minutes per slide/plate
Temperature Control
Programmable heating for both the spray nozzle and the heated sample tray drawer