
HTX M5 Sprayer
Equipment overview
The HTX M5 Sprayer is an advanced, automated matrix deposition system designed primarily for Mass Spectrometry Imaging (MSI) applications, such as MALDI-MSI sample preparation. Built on the foundation of previous models, the M5 features an upgraded chassis, high-velocity XY stage, and an integrated heated sample tray/drawer.
Major applications
Its primary purpose is to apply a precise, highly uniform coating of matrix solutions (or enzymes like trypsin for on-tissue digestion) onto tissue samples or MALDI plates. This guarantees fine crystal formation and optimal analyte extraction while minimizing analyte delocalization, yielding high spatial resolution and robust relative quantification.
Specifications
- Flow Rate Range
- 0.050 to 1.000 mL/min
- Gas Pressure
- 8 psi to 30 psi (Nitrogen)
- Nozzle Velocity
- Up to 5,600 mm/min via the High-Velocity XY stage
- Deposition Consistency
- ± 3% by weight across the total sample area
- Sample Preparation Time
- Typically 2 to 18 minutes per slide/plate
- Temperature Control
- Programmable heating for both the spray nozzle and the heated sample tray drawer


